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1

Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand

Scott E. Wolkenberg, Zhijian Zhao, Marianna Kapitskaya, Andrea L. Webber, Konstantin Petrukhin, Yui Sing Tang, Dennis C. Dean, George D. Hartman, Craig W. Lindsley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

2

A Microsatellite Genetic Linkage Map of Human Chromosome 13

Konstantin E. Petrukhin, Marcy C. Speer, Eftihia Cayanis, Maria de Fátima Bonaldo, Umadevi Tantravahi, Marcelo Bento Soares, Stuart G. Fischer, Dorothy Warburton, T.Conrad Gilliam, Jurg Ott

Journal:

Year:

1993

File:

PDF, 572 KB

1993

3

Dinucleotide repeat polymorphism at the D1S182 locus

Petrukhin, Konstantin E., Gilliam, T.Conrad

Journal:

Human Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 73 KB

english, 1992

4

A1120, a Nonretinoid RBP4 Antagonist, Inhibits Formation of Cytotoxic Bisretinoids in the Animal Model of Enhanced Retinal Lipofuscinogenesis

Dobri, Nicoleta, Qin, Qiong, Kong, Jian, Yamamoto, Kazunori, Liu, Zhao, Moiseyev, Gennadiy, Ma, Jian-xing, Allikmets, Rando, Sparrow, Janet R., Petrukhin, Konstantin

Journal:

Investigative Ophthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 622 KB

english, 2013

5

Preparation and characterization of calibration beads for sorting cells expressing a β-lactamase gene reporter

Michael E. Cunningham, Marianna Kapitskaya, Konstantin Petrukhin, Bohumil Bednar

Journal:

Cytometry Part A

Year:

2005

Language:

english

File:

PDF, 710 KB

english, 2005

6

Development of the High Throughput Screening Assay for Identification of Agonists of an Orphan Nuclear Receptor

Kapitskaya, Marianna, Cunningham, Michael E., Lacson, Raul, Kornienko, Oleg, Bednar, Bohumil, Petrukhin, Konstantin

Journal:

Assay and Drug Development Technologies

Year:

2006

Language:

english

File:

PDF, 2.45 MB

english, 2006

7

Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments

YANG, Xiao-Li, MIURA, Naoyuki, KAWARADA, Yoshihiko, TERADA, Kunihiko, PETRUKHIN, Konstantin, GILLIAM, T. Conrad, SUGIYAMA, Toshihiro

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 354 KB

english, 1997

8

[Topics in Medicinal Chemistry] || Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease

Petrukhin, Konstantin

Year:

2020

File:

PDF, 558 KB

2020

9

New therapeutic targets in atrophic age-related macular degeneration

Petrukhin, Konstantin

Journal:

Expert Opinion on Therapeutic Targets

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

10

Dinucleotide repeat polymorphism at the D4S251 locus

Petrukhin, Konstantin E., Modyanov, Nikolai N., Gilliam, T. Conrad

Journal:

Human Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 94 KB

english, 1992

11

Pharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment

Petrukhin, Konstantin

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2013

Language:

english

File:

PDF, 397 KB

english, 2013

12

Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey

Racz, Boglarka, Varadi, Andras, Pearson, Paul G., Petrukhin, Konstantin, Steinle, Jena J.

Journal:

Year:

2020

File:

PDF, 1.02 MB

2020

13

10.1038/915

Petrukhin, Konstantin, Wadelius, Claes, Koisti, Markus J., Bakall, Benjamin, Li, Wen, Xie, Guochun, Marknell, Towa, Sandgren, Ola, Forsman, Kristina, Holmgren, Gösta, Andreasson, Sten, Vujic, Mihailo,

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 376 KB

english, 1998

14

Retina-Specific Nuclear Receptor: A Potential Regulator of Cellular Retinaldehyde-Binding Protein Expressed in Retinal Pigment Epithelium and Muller Glial Cells

Fang Chen, David J. Figueroa, Alan D. Marmorstein, Qing Zhang, Konstantin Petrukhin, C. Thomas Caskey and Christopher P. Austin

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.80 MB

english, 1999

15

Genetic disorders of copper metabolism

Petrukhin, Konstantin, Gilliam, T. Conrad

Journal:

Current Opinion in Pediatrics

Year:

1994

File:

PDF, 368 KB

1994

16

A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration

Shin, Younghwa, Moiseyev, Gennadiy, Petrukhin, Konstantin, Cioffi, Christopher L., Muthuraman, Parthasarathy, Takahashi, Yusuke, Ma, Jian-xing

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2018

Language:

english

File:

PDF, 2.45 MB

english, 2018

17

Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities

Cioffi, Christopher L., Muthuraman, Parthasarathy, Raja, Arun, Varadi, Andras, Racz, Boglarka, Petrukhin, Konstantin

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.15 MB

2020

18

DPOFA, a Cl-/HCO3-exchanger antagonist, stimulates fluid absorption across basolateral surface of the retinal pigment epithelium

Pavel Iserovich, Qiong Qin, Konstantin Petrukhin

Journal:

BMC Ophthalmology

Year:

2011

Language:

english

File:

PDF, 262 KB

english, 2011

19

The mutation spectrum of the bestrophin protein – functional implications

B. Bakall, Towa Marknell, Sofie Ingvast, Markus J. Koisti, Ola Sandgren, Wen Li, Arthur A. B. Bergen, Sten Andreasson, Tomas Rosenberg, Konstantin Petrukhin, Claes Wadelius

Journal:

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

20

Dual role of Nr2e3 in photoreceptor development and maintenance

Andrea L. Webber, Paul Hodor, Catherine J. Thut, Thomas F. Vogt, Theresa Zhang, Daniel J. Holder, Konstantin Petrukhin

Journal:

Experimental Eye Research

Year:

2008

Language:

english

File:

PDF, 861 KB

english, 2008

21

In Vivo Effect of Mutant ELOVL4 on the Expression and Function of Wild-Type ELOVL4

Mandal, Nawajes A., Tran, Julie-Thu A., Zheng, Lixin, Wilkerson, Joseph L., Brush, Richard S., McRae, Joel, Agbaga, Martin-Paul, Zhang, Kang, Petrukhin, Konstantin, Ayyagari, Radha, Anderson, Robert E

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 729 KB

english, 2014

22

In Pursuit of Synthetic Modulators for the Orphan Retina-Specific Nuclear Receptor NR2E3

Qin, Qiong, Knapinska, Anna, Dobri, Nicoleta, Madoux, Franck, Chase, Peter, Hodder, Peter, Petrukhin, Konstantin

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

23

Haploinsufficiency Is Not the Key Mechanism of Pathogenesis in a Heterozygous Elovl4 Knockout Mouse Model of STGD3 Disease

Raz-Prag, Dorit, Ayyagari, Radha, Fariss, Robert N., Mandal, Md Nawajes A., Vasireddy, Vidyullatha, Majchrzak, Sharon, Webber, Andrea L., Bush, Ronald A., Salem, Norman, Petrukhin, Konstantin, Sieving

Journal:

Investigative Ophthalmology & Visual Science

Year:

2006

Language:

english

File:

PDF, 571 KB

english, 2006

24

Assessment of mutations in the best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull’s-eye maculopathy

Johanna M Seddon, Mehran A Afshari, Sanjay Sharma, Paul S Bernstein, Sandy Chong, Amy Hutchinson, Konstantin Petrukhin, Rando Allikmets

Journal:

Year:

2001

Language:

english

File:

PDF, 353 KB

english, 2001

25

A non-retinoid antagonist of Retinol-Binding Protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle

Racz, Boglarka, Varadi, Andras, Kong, Jian, Allikmets, Rando, Pearson, Paul G., Johnson, Graham, Cioffi, Christopher L., Petrukhin, Konstantin

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 2.17 MB

english, 2018

26

Gelastic epilepsy, hypothalamic hamartoma, precocious puberty, and agenesis of the corpus callosum: a new association

Alikchan A Alikchanov, Andrey S Petrukhin, Konstantin Yu Mukhin, Alexander Yu Nikanorov

Journal:

Brain and Development

Year:

1998

Language:

english

File:

PDF, 336 KB

english, 1998

27

Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase: genomic organization, alternative splicing, and structure/function predictions

Petrukhin, Konstantin, Lutsenko, Svetiana, Chernov, Igor, Ross, Barbara M., Kaplan, Jack H., Gilliam, T.Conrad

Journal:

Human Molecular Genetics

Year:

1994

Language:

english

File:

PDF, 5.91 MB

english, 1994

28

[Society of Petroleum Engineers SPE Arctic and Extreme Environments Technical Conference and Exhibition - Moscow, Russia (2013-10-15)] SPE Arctic and Extreme Environments Technical Conference and Exhibition - Well Flow Dynamic Modelling - the Tool to Optimize Well Operations

Konstantin, Petrukhin

Language:

english

File:

PDF, 541 KB

english

29

Heterologous Expression of the Metal-Binding Domains of Human Copper-Transporting ATPases (P1-ATPases)

SVETLANA LUTSENKO, KONSTANTIN PETRUKHIN, T. CONRAD GILLIAM, JACK H. KAPLAN

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 199 KB

english, 1997

30

10.1038/83817

Petrukhin, Konstantin, Zhang, Kang, Kniazeva, Marina, Han, Min, Li, Wen, Yu, Zhengya, Yang, Zhenglin, Li, Yang, Metzker, Michael L., Allikmets, Rando, Zack, Donald J., Kakuk, Laura E., Lagali, Pamela

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 371 KB

english, 2001

31

Dinucleotide repeat polymorphism at the D19S206 locus

Petrukhin, Konstantin E., Gilliam, T. Conrad

Journal:

Human Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 73 KB

english, 1992

32

[Society of Petroleum Engineers SPE Arctic and Extreme Environments Technical Conference and Exhibition - Moscow, Russia (2013-10-15)] SPE Arctic and Extreme Environments Technical Conference and Exhibition - Well Flow Dynamic Modelling - the Tool to Optimize Well Operations (Russian)

Konstantin, Petrukhin

Language:

russian

File:

PDF, 615 KB

russian

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